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Abstract We present Band 6 and Band 7 observations of 10 Lupus disks around M3-K6 stars from the Atacama Large Millimeter/submillimeter Array survey of Gas Evolution in PROtoplanetary disks (AGE-PRO) Large Program. In addition to continuum emission in both bands, our Band 6 setup covers the¹²CO,¹³CO, and C¹⁸OJ= 2–1 lines, while our Band 7 setup covers the N₂H⁺J= 3–2 line. All of our sources are detected in¹²CO and¹³CO; seven out of ten are detected in C¹⁸O; and three are detected in N₂H⁺. We find strong correlations between the CO isotopologue line fluxes and the continuum flux densities. With the exception of one disk, we also identify a strong correlation between the C¹⁸OJ= 2–1 and N₂H⁺J= 3–2 fluxes, indicating similar CO abundances across this sample. For the two sources with well-resolved continuum and¹²COJ= 2–1 images, we find that their gas-to-dust size ratio is consistent with the median value of ∼2 inferred from a larger sample of Lupus disks. We derive dust disk masses from continuum flux densities. We estimate gas disk masses by comparing C¹⁸OJ= 2–1 line fluxes with those predicted by the limited grid of self-consistent disk models of M. Ruaud et al. A comparison of these mass estimates with those derived by L. Trapman et al., using a combination of CO isotopologue and N₂H⁺line emission, shows that the masses are consistent with each other. Some discrepancies appear for small and faint disks, but they are still within the uncertainties. Both methods find gas disk masses increase with dust disk masses, and gas-to-dust mass ratios are between 10 and 100 in the AGE-PRO Lupus sample.